400 years in the future, after a virus decimates the world population, only one city on Earth remains. Ruled by the Goodchild dynasty, it is a perfect society of peace and prosperity - except that its citizens keep mysteriously disappearing.

Charlize Theron stars as "Aeon Flux," a secret agent/assassin/warrior whose mission is to bring down the regime. But as she goes deeper into her mission, Aeon uncovers some shocking secrets that put the mission and her life in danger.